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Rick Stewart didn't understand about the laburnum trees growing in Bulgaria and their potential to produce a drug for stopping smoking cigarettes back when he was the president of the pharmaceutical company Amarin. He was unfathomable inside the drug industry, a location often slammed for its short-sighted focus on profits.

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Just then might he identify the opportunity in those yellow-flowering trees. Now, with the help of the National Institutes of Health, Stewart is trying to introduce the laburnum-derived drug to the U.S. market. The tablet works by disrupting tobacco yearnings, much like Pfizer's top-selling Chantix, but possibly without that drug's high-profile side effects and at a much lower cost.

Today, researchers are excited about what might be the first new treatment for smoking cigarettes cessation to emerge in years. "We need this," said David Shurtleff, deputy director of the NIH Center for Complementary and Integrative Health, explaining why his company is assisting to get the drug authorized. But laburnum's guarantee is not brand-new.

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From left, Ronald Martell, Rick Stewart and Anthony Clarke of Extab. Stewart wishes to rebrand the smoking-cessation drug Tabex as Extab for sale in Western European and U.S. markets. (Tom Pilston) In 2007, Stewart had staked his job as the head of Amarin on a different drug. Miraxion was for dealing with Huntington's Disease, and early on it revealed indications of improving signs of the neurological disorder.

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Investors in Amarin, a $240 million business based in New Jersey, were shocked. The company's stock fell 80 percent. Stewart ran out a job. "The CEO constantly falls on his sword," Stewart, 56, states now. However Miraxion did appear to help patients with Huntington's it simply took longer than the six months set aside throughout the scientific trials.

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This led Stewart and Anthony Clarke, who likewise lost his job after running the trials for Amarin, to wonder what other misunderstood drugs were out there. They went on a hunt. "These drugs are uncared for or unwanted. They require tender loving care," Stewart says. "And pharma, for whatever factor, can't be troubled with them." cytisine smoking cessation established a tiny company outside London named Ricanto a mash-up of their given names.